Homeostatic Inflammation

Homeostatic Inflammation in Heart Disease
How inflammation is regulated in the heart and contributes to the transition from adaptive cardiac hypertrophy to heart failure will be discussed.
Mar 13, 2022 9:00 AM — 12:00 PM Kobe, Online
Project Project
Aging in Cardiovascular Medicine
Aging and cardiovascular disease will be discussed.
Jan 25, 2022 7:00 PM — 8:00 PM Tokyo, Online
Project
Pathogenic Basis of Thromboinflammation and Endothelial Injury in COVID-19: Current Findings and Therapeutic Implications
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global …
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Biodegradable Extremely-Small-Diameter Vascular Graft Made of Silk Fibroin can be Implanted in Mice
Aim, Synthetic vascular grafts are widely used in surgical revascularization, mainly for medium- to large-sized vessels. However, …
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Activation of Toll-Like Receptor 9 Impairs Blood Flow Recovery After Hind-Limb Ischemia
Background, Peripheral artery disease causes significant functional disability and results in impaired quality of life. Ischemic tissue …
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Toll-Like Receptor 9 Plays a Pivotal Role in Angiotensin II-Induced Atherosclerosis
Background Toll-like receptor ( TLR ) 9 recognizes bacterial DNA , activating innate immunity, whereas it also provokes inflammation in …
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Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue inflammation and insulin resistance
Obesity stimulates chronic inflammation in adipose tissue, which is associated with insulin resistance, although the underlying …
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Pioglitazone Reduces Vascular Lipid Accumulation in Angiotensin II-Induced Hypertensive Rat
Aim, In an insulin-resistant state, excess lipids may accumulate in various non-adipose tissues, leading to histological and functional …
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Endothelial PGC-1α mediates vascular dysfunction in diabetes
Endothelial dysfunction is a central hallmark of diabetes. The transcriptional coactivator PGC-1α is a powerful regulator of …
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HMGB1 plays a critical role in vascular inflammation and lesion formation via toll-like receptor 9
Objective, Endogenous ligands such as high-mobility group box 1 (HMGB1) and nucleic acids are released by dying cells and bind to …
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