Higashikuni Lab
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RNA Metabolism and Modification
RNA Metabolism and Modification in Cardiovascular disease
Deciphering RNA metabolism and modification in pathogenic mechanism of heart failure for development of novel therapeutic strategies.
BCVR2025 Linking inflammation to metabolic changes in heart disease
We will discuss inflammation and metabolism in heart disease.
Dec 14, 2025 10:00 AM — 12:00 PM
Kyoto
Yasutomi Higashikuni, M.D., Ph.D., FESC
Project
Project
Project
Compound heterozygous variants of CACNA1H change channel properties and contribute to intractable epilepsy with myoclonic-atonic seizures
The CACNA1H gene, which encodes the T-type calcium channel Cav3.2, is known to confer susceptibility to childhood absence epilepsy …
Ayumi Matsumoto
,
Go Kasuya
,
Suvd Tumurbaatar
,
Takuya Masuda
,
Kei Wakabayashi
,
Masako Kawada
,
Yasutomi Higashikuni, M.D., Ph.D., FESC
,
Kazuhiro Muramatsu
,
Koichi Nakajo
,
Hitoshi Osaka
,
Takayoshi Matsumura
Project
DOI
JCC2025 Cardiac inflammatory signaling in health and disease
We will discuss aging and inflammatory signaling in heart disease.
Sep 21, 2025 8:10 AM — 9:40 AM
Kochi
Yasutomi Higashikuni, M.D., Ph.D., FESC
Project
Project
Project
ESC2025 RNA metabolism in heart disease
We will discuss RNA metabolism in heart disease.
Aug 29, 2025 8:00 AM — 9:00 AM
Madrid
Yasutomi Higashikuni, M.D., Ph.D., FESC
Project
Project
Project
58th Lake Kawaguchi Conference of Cardiology Inflammatory signaling in heart disease
We will discuss aging and inflammatory signaling in heart disease.
Aug 24, 2025 9:50 AM — 11:00 AM
Tokyo
Yasutomi Higashikuni, M.D., Ph.D., FESC
Project
Project
Project
SHVM2025 RNA metabolism in heart disease
We will discuss RNA metabolism in heart disease.
Jun 23, 2025 11:45 AM — 12:00 PM
Bordeaux
Yasutomi Higashikuni, M.D., Ph.D., FESC
Project
Project
Project
Mitigation of Doxorubicin Cardiotoxicity With Synergistic miRNA Combinations Identified Using Combinatorial Genetics en masse (CombiGEM)
Background, Cardiomyocyte loss occurs in acute and chronic cardiac injury, including cardiotoxicity due to chemotherapeutics like …
Yasutomi Higashikuni, M.D., Ph.D., FESC
,
Colin Platt
,
Margaret H Hastings
,
William C W Chen
,
Justin R B Guerra
,
Takeshi Tokuyama
,
Fuad Gandhi Torizal
,
Wenhao Liu, M.D.
,
Takumi Obana
,
Abraham L Bayer
,
Hannah Whipple
,
lexandra Kuznetsov
,
Ashish Yeri
,
Cole Turissini
,
Robert R Kitchen
,
Kota Shibayama
,
Takayoshi Matsumura
,
Norihiko Takeda
,
Hideki Uosaki
,
Aarti H Asnani
,
Timothy K Lu
,
Anthony Rosenzweig
Project
DOI
Just published in JACC CardioOncology!!
Mitigation of Doxorubicin Cardiotoxicity With Synergistic miRNA Combinations Identified Using Combinatorial Genetics en masse (CombiGEM)
Yasutomi Higashikuni, M.D., Ph.D., FESC
Last updated on Jun 2, 2025
1 min read
Lab
Project
ISHR2025 Aging and inflammatory signaling in heart disease
We will discuss aging and inflammatory signaling in heart disease.
May 12, 2025 8:30 AM — 10:30 AM
Nara
Yasutomi Higashikuni, M.D., Ph.D., FESC
Project
Project
Project
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