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Synthetic Cardiology
Structure-function-guided exploration of the antimicrobial peptide polybia-CP identifies activity determinants and generates synthetic therapeutic candidates
Antimicrobial peptides (AMPs) constitute promising alternatives to classical antibiotics for the treatment of drug-resistant …
Marcelo D. T. Torres
,
Cibele N. Pedron
,
Yasutomi Higashikuni, M.D., Ph.D., FESC
,
Robin M. Kramer
,
Marlon H. Cardoso
,
Karen G. N. Oshiro
,
Octavio L. Franco
,
Pedro I. Silva Junior
,
Fernanda D. Silva
,
Vani X. Oliveira Junior
,
Timothy K. Lu
,
Cesar de la Fuente-Nunez
Project
DOI
Advancing therapeutic applications of synthetic gene circuits
Synthetic biology aims to introduce new sense-and-respond capabilities into living cells, which would enable novel therapeutic …
Yasutomi Higashikuni, M.D., Ph.D., FESC
,
William C.W. Chen
,
Timothy K. Lu
Project
Project
DOI
Discordance of the areas of peak wall shear stress and tissue stress in coronary artery plaques as revealed by fluid-structure interaction finite element analysis: a case study
Simulation studies have been performed in attempts to elucidate the signifi cance of shear and tissue stresses in the progression and …
Tatsuya Asanuma
,
Yasutomi Higashikuni, M.D., Ph.D., FESC
,
Hiroshi Yamashita
,
Ryozo Nagai
,
Toshiaki Hisada
,
Seiryo Sugiura
Project
DOI
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